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selected literature on urgency    
click on the title to jump to the abstract if available (titles in black)
urgency (urinary) - see also urgency (bowel)
  • Two types of urgency.
    Blaivas JG, Panagopoulos G, Weiss JP, Somaroo C. Neurourol Urodyn 2009;28:188-90.
    - the definition of urgency remains the subject of much controversy
    - the authors believe that urgency is comprised of at least two different sensations
    - distinction between them is important since they may have different etiologies and may respond differently to treatment
  • Goal achievement provides new insights into interstitial cystitis/painful bladder syndrome symptoms and outcomes.
    Payne C, Allee T. Neurourol Urodyn 2008;28:13-7
    - using the Goal Assessment Scaling (GAS) concept, the authors used surveys and focus groups to characterize the goals of patients with IC/PBS in order to create a pilot GAS
    - it was concluded that patients have individualized treatment goals; GAS holds promise for addressing individuality in a standardized format
    - a new instrument developed from this work is being piloted in a multicenter RCT
    - the authors also suggest that questionnaires investigating urgency in IC/PBS clarify the definition in a way more applicable to the specific condition
    - the groups defined urgency in IC/PBS as "the need to urinate due to an unpleasant sensation that prevents attention to any other task"
  • Evaluation of urgency in women, with a validated Urgency, Severity and Impact Questionnaire (USIQ).
    Lowenstein L, Fitzgerald MP, Kenton K, et al. Int Urogynecol J Pelvic Floor Dysfunct. 2008 Nov 20. [Epub ahead of print] PMID: 19020786

    - the aim of this study was to develop and validate a urinary urgency questionnaire to measure the severity and quality of life (QOL) impact from urinary urgency, in order to advance the clinical understanding of urinary urgency, and ultimately to guide the evaluation and treatment of patients with overactive bladder (OAB)
    - the USIQ comprises five symptom severity items and eight QOL items
    - click the title above for the full article (it is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited)
  • Assessing urgency in interstitial cystitis/painful bladder syndrome.   
    Diggs C, Meyer WA, Langenberg P, et al. Urology 2007;69:210-4
    - the O'Leary-Sant Symptom Index appeared to underreport urgency
    - asking about urgency "with little or no warning" underestimated the prevalence and degree of urinary urgency
    - the authors conclude with the question that may have pathophysiological importance: "why do patients with IC/PBS have urgency?"
  • The molecular basis of urgency: Regional difference of vanilloid receptor expression in the human urinary bladder.
    Liu L, Mansfield KJ, Kristiana I, et al. Neurourol Urodyn 2006 Oct 2; [Epub ahead of print]
    - the authors conclude that symptoms of sensory urgency were associated with the increased expression of targeting vanilloid receptor TRPV1 mRNA in the trigonal mucosa; no upregulation or regional differences of TRPV1 mRNA were seen in idiopathic detrusor overactivity patients
    - TRPV1 may play a role in SU and premature first bladder sensation on filling
urgency (bowel)
  • Bowel urgency in patients with irritable bowel syndrome.
    Basilisco G, De Marco E, Tomba C, Cesana BM. Gastroenterology 2006 Oct; [Epub ahead of print]
    - the authors conclude that the symptom of urgency is associated with objective alterations in the colonic and rectal reservoir of patients with irritable bowel syndrome.
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