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- Bladder pain syndrome/interstitial cystitis: a sense of urgency.
Hanno PM, Chapple CR, Cardozo LD. World J Urol 2009;27:717-21
- a review on bladder pain syndrome with special attention to urgency and overactive bladder
- Overactive bladder: a new paradigm.
Blaivas JG. Int Urogynecol J Pelvic Floor Dysfunct 2009 Oct 29. [Epub ahead of print] PMID: 19865783
- Measuring urgency in clinical practice.
Dmochowski RR, Fitzgerald MP, Wyndaele JJ. World J Urol 2009 Aug 27. [Epub ahead of print]
- Two types of urgency.
Blaivas JG, Panagopoulos G, Weiss JP, Somaroo C. Neurourol Urodyn 2009;28:188-90.
- the definition of urgency remains the subject of much controversy
- the authors believe that urgency is comprised of at least two different sensations
- distinction between them is important since they may have different etiologies and may respond differently to treatment
- Goal achievement provides new insights into interstitial cystitis/painful bladder syndrome symptoms and outcomes.
Payne C, Allee T. Neurourol Urodyn 2008;28:13-7
- using the Goal Assessment Scaling (GAS) concept, the authors used surveys and focus groups to characterize the goals of patients with IC/PBS in order to create a pilot GAS
- it was concluded that patients have individualized treatment goals; GAS holds promise for addressing individuality in a standardized format
- a new instrument developed from this work is being piloted in a multicenter RCT
- the authors also suggest that questionnaires investigating urgency in IC/PBS clarify the definition in a way more applicable to the specific condition
- the groups defined urgency in IC/PBS as "the need to urinate due to an unpleasant sensation that prevents attention to any other task"
- Evaluation of urgency in women, with a validated Urgency, Severity and Impact Questionnaire (USIQ).
Lowenstein L, Fitzgerald MP, Kenton K, et al. Int Urogynecol J Pelvic Floor Dysfunct. 2008 Nov 20. [Epub ahead of print] PMID: 19020786
- the aim of this study was to develop and validate a urinary urgency questionnaire to measure the severity and quality of life (QOL) impact from urinary urgency, in order to advance the clinical understanding of urinary urgency, and ultimately to guide the evaluation and treatment of patients with overactive bladder (OAB)
- the USIQ comprises five symptom severity items and eight QOL items
- click the title above for the full article (it is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited)
- The molecular basis of urgency: regional differences of vanilloid receptor expression in the human urinary bladder.
Liu L, Mansfield KJ, Kristiana I, et al. Neurourol Urodyn 2007;26:433-8
editorial comment
Cruz F.Neurourol Urodyn 2007;26:439
- Overactive bladder and the definition of urgency.
Blaivas JG. Neurourol Urodyn. 2007 May 4; [Epub ahead of print]
editorial comment
Abrams P. Neurourol Urodyn 2007 Jun 11;[Epub ahead of print]
author's reply
Blaivas J. Neurourol Urodyn 2007 Jun 11; [Epub ahead of print]
- Assessing urgency in interstitial cystitis/painful bladder syndrome.
Diggs C, Meyer WA, Langenberg P, et al. Urology 2007;69:210-4
- the O'Leary-Sant Symptom Index appeared to underreport urgency
- asking about urgency "with little or no warning" underestimated the prevalence and degree of urinary urgency
- the authors conclude with the question that may have pathophysiological importance: "why do patients with IC/PBS have urgency?"
- The molecular basis of urgency: Regional difference of vanilloid receptor expression in the human urinary bladder.
Liu L, Mansfield KJ, Kristiana I, et al. Neurourol Urodyn 2006 Oct 2; [Epub ahead of print]
- the authors conclude that symptoms of sensory urgency were associated with the increased expression of targeting vanilloid receptor TRPV1 mRNA in the trigonal mucosa; no upregulation or regional differences of TRPV1 mRNA were seen in idiopathic detrusor overactivity patients
- TRPV1 may play a role in SU and premature first bladder sensation on filling
- Using the International Continence Society’s definition of painful bladder syndrome.
Warren JW, Greenberg P, Meyer WA, et al. Urology 2006;67:1138-42
- Localization of the urge to void in patients with painful bladder syndrome.
FitzGerald MP, Kenton KS, Brubaker L. Neurourol Urodyn 2005;24:633-7
- Validation of the urgency perception scale
Cardozo L, Coyne KS, Versi E. BJU Int 2005;95:591-6
- The
role of urinary urgency and its measurement in the overactive bladder
symptom syndrome: current concepts and future prospects
Chapple CR, Artibani W, Cardozo LD, et al. BJU Int 2005;95:335-40
- How urgent is urgency? A review of current
methods of assessment
Freeman RM. Int Urogynecol J Pelvic Floor Dysfunct 2005;16:93-5 [PMUI: 15789143]
- The urgency of the problem and the problem of urgency in the overactive bladder.
Chapple CR, Wein AJ. BJU Int 2005;95:274-5
- Urgency: the key to defining the overactive bladder.
Abrams P. BJU Int 2005;96 (Suppl 1):1:3
- Overactive bladder and painful bladder syndrome: there need not be confusion.
Abrams P, Hanno P, Wein A. Neurourol Urodyn 2005;24:149-50
- Validation of Spanish version of Pelvic pain and urgency/Frequency (PUF) patient symptom scale.
Minaglia S, Ozel B, Nguyen JN, et al. Urology 2005;65:664-9
- How urgent is urgency ? A review of current methods of assessment.
Freeman RM. Int Urogynecol J Pelvic Floor Dysfunct 2005;16:93-5
- What is the pain of interstitial cystitis like?
FitzGerald MP, Brensinger C, Brubaker L, et al. Int Urogynecol J 2005;17:69-72
- Defining overactive bladder: epidemiology and burden of disease
Tubaro A. Urology 2004;64(Suppl 1):2-6
- Urgency: the cornerstone symptom of overactive bladder
Brubaker L. Urology 2004;64(Suppl 1):12-6
- The standardisation of terminology of lower urinary tract function: Report from the Standardisation Sub-committee of the international continence society.
Abrams P, Cardozo L, Griffiths D, et al. Am J Obstet Gynecol 2002;187:116-26
- Do women with idiopathic sensory urgency have early interstitial cystitis?
Frazer MI, Haylen BT, Sissons M. Br J Urol 1990;66:274-8
- the authors conclude that early interstitial cystitis should be considered as a possible cause of lower urinary tract symptoms in patients with apparently idiopathic sensory urgency.
- Bowel urgency in patients with irritable bowel syndrome.
Basilisco G, De Marco E, Tomba C, Cesana BM. Gastroenterology 2006 Oct; [Epub ahead of print]
- the authors conclude that the symptom of urgency is associated with objective alterations in the colonic and rectal reservoir of patients with irritable bowel syndrome.