selected literature on cross-talk/cross-organ interaction
Sensitization of pelvic nerve afferents and mast cell infiltration in the urinary bladder following chronic colonic irritation is mediated by neuropeptides. Ustinova EE, Gutkin DW, Pezzone MA. Am J Physiol Renal Physiol 2007;292(1):F123-30
PMID: 16926445
Convergence of bladder and colon sensory innervation occurs at the primary afferent level. Christianson JA, Liang R, Ustinova EE, et al. Pain 2006 Oct 26; [Epub ahead of print]
PMID: 17070995
Colonic irritation in the rat sensitizes urinary bladder afferents to mechanical and chemical stimuli: an afferent origin of pelvic organ cross-sensitization. Ustinova EE, Fraser MO, Pezzone MA. Am J Physiol Renal Physiol 2006;290(6):F1478-87
PMID: 16403832
Hyperexcitability of convergent colon and bladder dorsal root ganglion neurons after colonic inflammation: mechanism for pelvic organ cross-talk. Malykhina AP, Qin C, Greenwood-van Meerveld B, et al. Neurogastroenterol Motil 2006;18:936-48
PMID: 16961697
Cross-organ sensitization of lumbosacral spinal neurons receiving urinary bladder input in rats with inflamed colon. Qin C, Malykhina AP, Akbarali HI, Foreman RD. Gastroenterology 2005;129:1967-78
PMID: 16344065
A model of neural cross-talk and irritation in the pelvis: implications for the overlap of chronic pelvic pain disorders. Pezzone MA, Liang R, Fraser MO. Gastroenterology 2005;128:1953-64
PMID: 15940629
