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Selected literature from 2004 and earlier

therapy Epidural spinal cord stimulation for interstitial cystitis [Article in Spanish]
Pelaez E, Prieto Rodrigo MA, Munoz Zurdo MM, et al. Rev Esp Anestesiol Reanim 2004;51:549-52
  Die stationäre urologische Rehabilitation bei interstitieller Cystitis.
W. Vahlensieck. Der Urologe A (Issue: Online First) [Article in German]
• this paper describes results of a multidisciplinary approach to the urgency, frequency, nocturia and pain in IC patients.
  Modified Thiele massage as therapeutic intervention for female patients with interstitial cystitis and high-tone pelvic floor dysfunction.
Oyama IA, Rejba A, Lukban JC, et al. Urology 2004;64:862-8
  Botulinum toxin A has antinociceptive effects in treating interstitial cystitis.
Smith CP, Radziszewski P, Borkowski A, et al. Urology 2004;64:871-5
  Transdermal posterior tibial nerve laser therapy is not effective in women with interstitial cystitis.
O'Reilly BA, Dwyer PL, Hawthorne G, et al. J Urol 2004;172:1880-3
  A pilot clinical trial of oral pentosan polysulfate and oral hydroxyzine in patients with interstitial cystitis
Sant GR, Propert KJ, Hanno PM, et al. J Urol 2003;170:810-5.
  Treatment of interstitial cystitis.
Chancellor MB, Yoshimura N. Urology 2004;63(suppl 1):85-92
  Initial, long-term, and durable responses to terazosin, placebo, or other therapies for chronic prostatitis/chronic pelvic pain syndrome.
Cheah PY, Liong ML, Yuen KH, et al. Urology 2004;64:881-6
  Patient-adjusted intermittent electrostimulation for treating stress and urge urinary incontinence.
Nissenkorn I, Shalev M, Radziszewski P, et al. BJU Int 2004;94:105-9
  Urinary urgency and frequency, and chronic urethral and/or pelvic pain females. Can doxycycline help?
Burkhard FC, Blick N, Hochreiter WW, et al. J Urol 2004;172:232-5
  A prospective, randomized, placebo controlled, double-blind study of amitriptyline for the treatment of interstitial cystitis.
van Ophoven A, Pokupic S, Heinecke A, et al. J Urol 2004;172:533-6

Posterior tibial nerve stimulation in patients with intractable interstitial cystitis.
Zhao J, Nordling J. BJU Int 2004;94:101-4.
• intermittent percutaneous posterior tibial nerve stimulation in patients with refractory interstitial cystitis has no significant clinical effect over 10 weeks of treatment.

  Long-term outcome of patients with interstitial cystitis treated with low dose cyclosporine A.
Sairanen J, Forsell T, Ruutu M. J Urol 2004;171:2138-41.
• the initial cyclosporine dose: 3 mg/kg divided into 2 daily dosages; this was an open trial, a randomized trial is now being performed
  Patient-adjusted intermittent electrostimulation for treating stress and urge urinary incontinence.
Nissenkorn I, Shalev M, Radziszewski P, et al. BJU Int 2004;94:105-9
  Sacral neuromodulation for the treatment of refractory interstitial cystitis: outcomes based on technique.
Peters KM, Carey JM, Konstandt DB. Int Urogynecol J Pelvic Floor Dysfunct 2003;14:223-8
  The use of electrical devices for the treatment of bladder dysfunction: a review of methods.
van Balken MR, Vergunst H, Bemelmans BL. J Urol 2004;172:846-51
  Caecocystoplasty for intractable interstitial cystitis: long-term results.
Chakravarti A, Ganta S, Somani B, et al. Eur Urol 2004;46:114-7
  Hyperbaric oxygen for the treatment of interstitial cystitis: long-term results of a prospective pilot study.
van Ophoven A, Rossbach G, Oberpenning F, et al. Eur Urol 2004;46:108-13
  Hypersensitivity reaction associated with intravesical Bacillus Calmette-Guerin for interstitial cystitis.
Parker C, Steele S, Raghavan R, et al. J Urol 2004;172:537
  Sacral neuromodulation decreases narcotic requirements in refractory interstitial cystitis.
Peters KM, Konstandt D. BJU Int 2004;93:777-9
  Current strategies for managing interstitial cystitis.
Parsons CL. Expert Opin Pharmacother 2004;5:287-93
  Assessing self-help issues for patients with prostate cancer, interstitial cystitis, erectile dysfunction and urinary diversion.
Breau RH, McGrath PJ, Norman RW. BJU Int 2003;92:736-40
symptoms Different clinical presentation of interstitial cystitis syndrome.
Porru D, Politano R, Gerardini M, et al. Int Urogynecol J Pelvic Floor Dysfunct 2004;15:198-202.
diagnosis Future research needs for the definition/diagnosis of interstitial cystitis.
Bade J, Ishizuka O, Yoshida M. Int J Urol 2003;10(suppl):S31-4
  Interstitial cystitis: modern tools for an accurate diagnosis.
Nipkow L, Chai TC. Curr Urol Rep 2003;4:381-4
  Intravesical potassium chloride sensitivity test in men with chronic pelvic pain syndrome.
Yilmaz U, Liu YW, Rothman I, et al. J Urol 2004;172:548-50
  Interstitial cystitis. New aspects in diagnosis and therapy.
[article in German] Loch A, Stein U. Urologe A. 2004;43:1135-46

A referral center's experience with transitional cell carcinoma misdiagnosed as interstitial cystitis.
Tissot WD, Diokno AC, Peters KM. J Urol 2004;172:478-80


Primary evaluation of patients suspected of having interstitial cystitis (IC).
Nordling J, Anjum FH, Bade JJ, et al. Eur Urol 2004;45:662-9.

summary pdf
  Interstitial cystitis: how should we diagnose it and treat it in 2004 ?
Nordling J. Curr Opin Urol 2004;14:323-7
aetiology & pathogenesis Interstitial cystitis antiproliferative factor (APF) as a cell-cycle modulator.
Rashid HH, Reeder JE, O'Connell MJ, et al. BMC Urol 2004;4:3
  Possible mechanisms inducing glomerulations in interstitial cystitis: relationship between endoscopic findings and expression of angiogenic growth factors.
Tamaki M, Saito R, Ogawa O, et al. J Urol 2004;172:945-8
  Expression of intercellular adhesion molecules in the bladder of patients with interstitial cystitis.
Green M, Filippou A, Sant G, et al. Urology 2004;63:688-93.
  Interstitial cystitis: a review of immunological aspects of the aetiology and pathogenesis, with a hypothesis.
van de Merwe JP, Arendsen HJ. BJU Int 2000;85:995-9.
other cystitis Eosinophilic cystitis induced by penicillin.
Tsakiri A, Balslev I, Klarskov P. Int Urol Nephrol 2004;36:159-61
• a 30-year-old woman developed classic symptoms of painful bladder disease and eosinophilic cystitis as an adverse effect of penicillin for abdominal actinomycosis. The symptoms were reversible after stopping penicillin.
  Eosinophilic cystitis after bladder instillation with dimethyl sulfoxide.
Abramov Y, Goldberg RP, McGuire M, et al. Urology 2004;63:1182-3
  Is there an ethnic difference in the prevalence of lupus cystitis? A report of six cases.
Chen MY, Lee KL, Hsu PN, et al. Lupus 2004;13:263-9
overactive bladder Defining overactive bladder: epidemiology and burden of disease.
Tubaro A. Urology 2004;64(Suppl 1):2-6
The urothelium in overactive bladder: passive bystander or active participant?
de Groat WC. Urology 2004;64 (Suppl 1):7-11
Urgency: the cornerstone symptom of overactive bladder.
Brubaker L. Urology 2004;64(Suppl 1):12-6
The patient's perspective: redefining end points.
Palmtag H. Urology 2004;64(Suppl 1):17-20
Update on nocturia: the best of rest is sleep.
Marschall-Kehrel D. Urology 2004;64(Suppl 1):21-4
  Passive transfer of Sjögren's syndrome IgG produces the pathophysiology of overactive bladder.
Wang F, Jackson MW, Maughan V, et al. Arthritis Rheum 2004;50:3637-45
  Post-void residual urine volume in women with overactive bladder symptoms.
Milleman M, Langenstroer P, Guralnick ML. J Urol 2004;172:1911-4
related disorders A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder.
Arnold LM, Lu Y, Crofford LJ, et al. Arthritis Rheum 2004;50:2974-84
• in this trial, duloxetine (an antidepressant drug that is also used for overactive bladder and stress incontinence) was an effective and safe treatment for many of the symptoms associated with fibromyalgia in subjects with or without major depressive disorder, particularly for women, who had significant improvement across most outcome measures.
  Interstitial cystitis, chronic nonbacterial prostatitis and chronic pelvic pain syndrome in men: a common and frequently identical clinical entity.
Forrest JB, Schmidt S. J Urol 2004;172:2561-2
  Comorbidity of interstitial cystitis with other unexplained clinical conditions.
Buffington CA. J Urol 2004;172:1242-8
  Nonbladder related symptoms in patients with interstitial cystitis.
Erickson DR, Morgan KC, Ordille S, et al. J Urol 2001;166:557-61
  Mechanisms in prostatitis/chronic pelvic pain syndrome.
Pontari MA, Ruggieri MR. Urol 2004;172:839-45
  Physiopathologic relationship between interstitial cystitis and rheumatic, autoimmune, and chronic inflammatory diseases. [Article in Spanish] Lorenzo Gomez MF, Gomez Castro S. Arch Esp Urol 2004;57:25-34  
  Systemic aspects of interstitial cystitis, immunology and linkage with autoimmune disorders.
van de Merwe JP, Yamada T, Sakamoto Y. Int J Urol 2003;10 (suppl):S35-8
education EAU Update Series, December 2004 Volume 2, Issue 4, Pages 151-195: Neurourology
• new understanding of central and peripheral interaction between bladder and sphincter function 
• comparison of peripherally acting substance for treatment of detrusor overactivity: what is new; what is in the pipeline?
• botox in urology: a new treatment modality without limitations?
• pelvic pain and interstitial cystitis: therapeutic strategies, results and limitations
• neuromodulation -sacral, peripheral and central: current status, indications, results and new developments 
  Case of the month. Interstitial cystitis.
Smith JL. JAAPA 2004;17:48
  EAU guidelines on chronic pelvic pain.
Fall M, Baranowski AP, Fowler CJ, et al. EAU. Eur Urol 2004;46:681-9
• new amended summary.
mast cells Protease activated receptor stimulation activates a calcium-independent phospholipase A2 in bladder microvascular endothelial cells.
Rickard A, Portell C, Kell PJ, Vinson SM, McHowat J. Am J Physiol Renal Physiol. 2004; Nov 23; [epub ahead of print]
  An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide.
Keay SK, Szekely Z, Conrads TP, et al. Proc Natl Acad Sci USA 2004;101:11803-8
  Panic disorder, interstitial cystitis, and mast cells.
Theoharides TC. J Clin Psychopharmacol 2004;24:361-4
Is urine methylhistamine a useful marker for interstitial cystitis ?
Erickson DR, Kunselman AR, Bentley CM, et al. J Urol 2004 ;172:2256-60
Nitric oxide as an objective marker for evaluation of treatment response in patients with classic interstitial cystitis.
Hosseini A, Ehren I, Wiklund NP. J Urol 2004;172:2261-5
  Antiproliferative factor, heparin-binding epidermal growth factor-like growth factor, and epidermal growth factor in men with interstitial cystitis versus chronic pelvic pain syndrome.
Keay S, Zhang CO, Chai T, et al. Urology 2004;63:22-6
  Interstitial cystitis antiproliferative factor (APF) as a cell-cycle modulator.
Rashid HH, Reeder JE, O'Connell MJ, et al. BMC Urol 2004;4:3
prevalence Prevalence of interstitial cystitis in young women.
Parsons CL, Tatsis V. Urology 2004;64:866-70
• the investigators identified probable IC in 30.6% and documented IC in a minimum of 10% of the female medical students.
  Prevalence of interstitial cystitis in first-degree relatives of patients with interstitial cystitis.
Warren JW, Jackson TL, Langenberg P, et al.  Urology 2004;63:17-21
various Interstitial cystitis in persistent posthysterectomy chronic pelvic pain
Chung MK. JSLS 2004;8:329-33
  Is questionnaire enough to assess number of nocturic episodes ? : Prospective comparative study between data from questionnaire and frequency-volume charts.
Ku JH, Hong SK, Kim HH, et al. Urology 2004;64:966-9
  Detrusor overactivity, does it represent a difference if patients feel the involuntary contractions?
Wyndaele J-J, van Meel TD, de Wachter S. J Urol 2004;172:1915-8


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